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What Neuroanatomic Changes Are Seen In Individuals With Alzheimer's Disease

What Neuroanatomic Changes Are Seen In Individuals With Alzheimer's DiseaseSignificant modifications to the structure and operation of the brain mark a progressive neurodegenerative ailment called Alzheimer's. Finding effective treatments requires an understanding of these neuroanatomical changes. In this article, we'll look at the neuroanatomic alterations that people with Alzheimer's disease experience and talk about how Shilajit might help with treatment.

Changes in Neuroanatomy in Alzheimer's Disease

Brain atrophy: 

Brain atrophy is one of the distinctive neuroanatomical abnormalities of Alzheimer's disease. The hippocampus, which is essential for memory, and the cortex, which is in charge of cognition, are only two of the parts of the brain that are impacted by the shrinkage of the brain over time.

Amyloid Plaques: 

Amyloid plaques are created when beta-amyloid protein builds up in the brain. These plaques, a significant pathogenic aspect of Alzheimer's, interfere with brain connectivity.

Neurofibrillary Tangles: 

Abnormalities in the tau protein lead to the development of neurofibrillary tangles, which disrupt the microtubules in the brain, affecting cell function and ultimately causing cell death.

Neuroinflammation is a common symptom of Alzheimer's disease and activated microglia and higher cytokine production cause neuronal damage.

Impaired Blood Flow: 

Vascular abnormalities in the brain can reduce blood flow, further impairing cognitive performance.

A Potential Treatment: Shilajit

Shilajit, a naturally occurring resin-like substance from the Himalayan region, has drawn attention because of its possible health advantages, especially its effect on cognitive function. Despite the lack of studies on Shilajit's effects on Alzheimer's, it has a number of qualities that might be important:

Shilajit has a lot of antioxidants, which can lower oxidative stress in the brain and lessen the harm brought on by aberrant beta-amyloid and tau protein levels.

Effects on Neuroinflammation: Shilajit has anti-inflammatory characteristics that may help control neuroinflammation and promote neuroprotection.

Shilajit is thought to improve memory and cognitive function, which can be helpful for those with Alzheimer's disease.


Profound neuroanatomical alterations caused by Alzheimer's disease have an impact on both the structure and operation of the brain. Brain atrophy, the development of amyloid plaques and neurofibrillary tangles, inflammation, and reduced blood flow are some of these alterations. In order to find successful treatments, it is imperative to comprehend these modifications.

Although Shilajit's antioxidant, anti-inflammatory, and cognitive-enhancing characteristics show promise in sustaining cognitive health, it should not be considered a cure or treatment for Alzheimer's disease on its own. The management of Alzheimer's disease often entails a multimodal strategy that includes medication, dietary changes, and assistance for caregivers.

Alzheimer's patients should speak with medical specialists to create a thorough treatment plan that is suited to their unique requirements and situation. When taken into account as a component of a comprehensive strategy for managing Alzheimer's, Shilajit may provide possible assistance in preserving cognitive health.

Finally, the complexity of Alzheimer's disease is highlighted by the neuroanatomic changes that occur. Shilajit is one complementary therapy that should be investigated within the context of evidence-based care in order to offer hope and support to those who are dealing with this challenging neurological illness.



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